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Tuberculosis: The Good, The Bad and The Unfinished!

Tuberculosis (TB) has been with humans since time immemorial. We have been trying to get rid of TB since centuries. Have we done enough? Of course not! TB is still the leading cause of death. What can be done to eliminate TB? This could be a wrong question to ask. We must ask ourselves, what have we done till date and what more can be done to prevent huge loss to mankind from TB. This article gives an account of what has been done so far (the good!); where did we go wrong (the bad!); and what must be done (the unfinished!) to decrease the burden of TB, in India. Let’s start with the progress made thus far, or the “good”. India has come a long way from starting a National TB Program in 1962 (mainly for hospitalizing treatment) to rolling out Revised National TB Program (RNTP) in 1993 and Revised National TB Control Program (RNTCP) in 1997 to achieving its nationwide coverage by 2006.  The national programs imbibed the WHO’s Direct Observed Therapy Shortcourse (DOTS) Str

Rewards In Science: What Do They Do To Scientists?


On 26th September every year, all the young and not so young scientists of India eagerly wait for the announcement of the most prestigious scientific award – the Shanti Swarup Bhatnagar (SSB) Prize. The prize is awarded by Council of Scientific and Industrial Research (CSIR) since 1958 and given to Indian scientists below the age of 45, in seven scientific disciplines for their outstanding scientific work in India, both fundamental and applied, carried out preferably during last 5 years. It is interesting to note that so far, only 493 scientists have received this award of which I think 23 have gone on to become Fellows of the Royal Society. The SSB prize, needless to say is treated as the Indian Nobel Prize.

When I was a young faculty, I remember having a poster in my laboratory that would attract the attention of the students and which read “Keep ten minutes of your day to dream about the Nobel Prize”. In the month of October, all the leading researches of the world, aspiring for the Nobel Prize wait eagerly for the announcement from Stockholm. I don’t know how many will have the confidence of Sir C.V Raman, who could book his passage in advance, in the month of July, anticipating that he will win the Nobel, which is normally announced in October and given away in mid-December. On the contrary, the Nobel Prize eluded his student G. N Ramachandran (definitely a Nobel Prize deserving Indian scientist), throughout his life, despite being nominated more than once for the Nobel Prize. I have witnessed how disappointed and frustrated he was leading to emotional instability for being denied a prize which he truly deserved. Therefore the question – “Does awards in science do good to the scientists or otherwise” is debatable. While on one hand it can act as a great motivator, simultaneously the mismatch between expectations and rewards can be a source of great stress. All the reward systems are based on a third party opinion who judges the merit of a researcher. In my opinion, surrendering ones happiness and contentment of work in the hands of others is a sad affair for the scientific community. 

The merits and demerits of awards and rewards system, has been debated in all societies, especially in the field of science where it act as a double edged weapon. In my personal case, immediately post PhD, I received the INSA Young Scientist Award, along with Manju Bansal, student of Prof. G. N Ramachandran. This kept me back in India to pursue science. I understand that very large percentage (~75%) of INSA Young Scientist medal recipients have stayed back in India to pursue science, many of whom (98 out of 708 since 1974) have been eventually elected as the fellows of the Indian National Science Academy. Statistics shows clearly that early recognition acts as a motivator.

Later during 1990, I was thinking of moving to USA to participate in the Human Genome Project (HGP) at the Berkeley Lawrence Livermore lab, on the invitation of Prof. Charles Cantor, who had moved from Columbia University, New York to Berkeley. Realizing that neither Government of India nor Indian Institute of Science will be able to support my participation in HGP, I decided to move away to the ‘land of opportunity’. But the destiny spelled otherwise. On this day (26th Sep) in 1990, when I was 38 years old, the then DG, CSIR announced the list of winners of the Bhatnagar Award in which my name appeared. Receiving this recognition created a huge sense of responsibility which got firmed up by the innumerable letters and personal wishes I received. This single event made me think about the fairness of me leaving India when the country has recognized whatever little science I have done. And that dissuaded me from accepting the offer. 

In my long scientific journey I have seen how aspirations for recognitions lead to distortion of scientific behavior. I have seen young and senior scientists lose their ethical values in pursuing science. The purpose of science gets converted to that of chasing awards. It is funny that every single award in scientific system in India increases the probability of a subsequent award. Therefore, while on one hand, it is very important to recognize scientists and treat them as heroes in the eyes of the public; simultaneously it is also important that the entire objectivity of selecting such individuals is not lost in patronizing loyalty above merit. 

I was very fortunate to have been elected to all the four science and engineering academies of India, at a reasonably young age. This indeed has kept me motivated to pursue science at a higher level. Unfortunately we have not guided our younger generation of researchers that pursuing science as a hobby with a purpose in mind is far more enjoyable than target oriented chasing of rewards and recognitions. 

Therefore while scientific awards have done a significant amount of good to the Indian scientific community both financially and otherwise, they have also created distortion in the system where receiving an award has become a mandate.

Today I salute those who have been conferred the prestigious Shanti Swarup Bhatnagar Prize for their accomplishments, but only to remind them that any recognition of the nation brings with it, larger level of responsibility and expectations from the society. While this award is given for individual excellence, one should remember that it also acts as a deterrent to collaborative efforts. As we have moved into this century, collaborative research has become centre stage of the interface of science. Simple discoveries like Graphene, for which two individuals could be given Nobel Prize, I wonder why for the same work done collaboratively by two young scientists, the Indian Nobel Prize cannot be shared. I feel our award committees should recognize collaborative research and credit multiple collaborators or individual researchers for achieving a scientific milestone, which is world recognizant. Very often it is debated as to how award and recognitions often goes to few who are already awarded and rewarded substantially and collaborative research is missed out. Therefore democratization and wide spread distribution of awards and rewards will take Indian science a long way. It is more true when 500 ISRO scientists working together for 18 months have achieved an impossible feat like Mission to Mars (Mangalyaan) in the maiden effort to make India proud, clearly indicating the power of many over individuals. 


Lesson from life’s experience 

I would like to express my life’s lessons at the end of this blog, through some quotable quotes by Nobel laureates:

“Discovery consists of looking at the same thing as everyone else and thinking something different.” 

                                                                                  ― Albert Szent-Györgyi

“It is open to every man to choose the direction of his striving; and also every man may draw comfort from Lessing's fine saying, that the search for truth is more precious than its possession.” 

                                                                                          ― Albert Einstein

“……………..Before they can secure possible working conditions, scientists have to exhaust their youth and their powers in daily anxieties. Our society, in which reigns an eager desire for riches and luxury, does not understand the value of science. It does not realize that science is a most precious part of its moral patrimony. Nor does it take sufficient cognizance of the fact that science is at the base of all the progress that lightens the burden of life and lessens its suffering. Neither public powers nor private generosity actually accord to science and to scientists the support and the subsidies indispensable to fully effective work.” 

                                                                                              ― Marie Curie

Although in pre-independent India, Indian scientists were receiving the best salaries in the British Raj (Reference: In Pursuit of Excellence: A History of the Indian Institute of Science by B V Subbarayappa) what Madame Marie Curie said, was true for the scientists in post-independent India. It is only in the recent years that things have started to change. However, in order to attract the best minds to this noble profession of science, one need to truly recognize, reward and award those men and women of science who make discoveries that lighten the path of millions. 



SKBlog-06

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